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. Author manuscript; available in PMC: 2020 Sep 20.
Published in final edited form as: Curr Cancer Drug Targets. 2020;20(4):253–270. doi: 10.2174/1568009619666191202101330

Fig. 8.

Fig. 8.

Structures of C-terminal Hsp90 inhibitors – The aminocoumarin antibiotic A) novobiocin derived from Steptomyces niveus and its analogue B) KU174. Compounds in this class share three common moieties: benzoic acid derivative, coumarin residue, and sugar novobiose.