Table 4.
Model-estimated delta values (Δ) for leukocyte counts and CRP, by trimester and population
| Measure | Population | Unit | T1–cycling Δ | T2–cycling Δ | T3–cycling Δ |
|---|---|---|---|---|---|
| Total leukocytes | NHANES | cells/µl | 1058 (552, 1591) | 2183 (1756, 2594) | 2048 (1641, 2448) |
| % | 15.1% (7.8%, 22.8%) | 31.1% (24.9%, 37.1%) | 29.2% (23.2%, 34.9%) | ||
| THLHP | cells/µl | 285 (−277, 838) | −121 (−596, 364) | −350 (−805, 118) | |
| % | 3.0% (−2.9%, 8.9%) | −1.3% (−6.3%, 3.9%) | −3.7% (−8.5%, 1.3%) | ||
| Neutrophils | NHANES | cells/µl | 1203 (781, 1637) | 2580 (2210, 2941) | 2500 (2141, 2886) |
| % | 30.3% (19.5%, 41.3%) | 65.0% (55.5%, 74.4%) | 63.0% (53.7%, 72.9%) | ||
| THLHP | cells/µl | 410 (13, 815) | 934 (561, 1319) | 989 (613, 1372) | |
| % | 8.4% (0.3%, 16.7%) | 19.3% (11.6%, 27.5%) | 20.5% (12.5%, 28.4%) | ||
| Lymphocytes | NHANES | cells/µl | −219 (−348, −78) | −343 (−441, −238) | −497 (−585, −402) |
| % | −10.0% (−15.9%, −3.6%) | −15.7% (−20.1%, −11.0%) | −22.8% (−26.7%, −18.6%) | ||
| THLHP | cells/µl | −73 (−254, 101) | −584 (−717, −455) | −580 (−705, −448) | |
| % | −2.7% (−9.2%, 3.7%) | −21.3% (−25.9%, −16.7%) | −21.2% (−25.5%, −16.5%) | ||
| Eosinophils | NHANES | cells/µl | 8 (−31, 55) | −31 (−55, −4) | −37 (−60, −9) |
| % | 4.2% (−17.0%, 30.3%) | −17.0% (−29.5%, −2.1%) | −19.8% (−32.4%, −5.0%) | ||
| THLHP | cells/µl | 87 (−142, 364) | −264 (−421, −93) | −499 (−635, −353) | |
| % | 7.2% (−11.9%, 30.1%) | −22.0% (−34.3%, −7.7%) | −41.7% (−51.1%, −30.3%) | ||
| Monocytes | NHANES | cells/µl | 45 (4, 85) | 49 (20, 81) | 105 (72, 138) |
| % | 9.0% (0.9%, 17.3%) | 10.0% (4.0%, 16.5%) | 21.2% (14.6%, 28.1%) | ||
| THLHP | cells/µl | 0 (−132, 164) | 0 (−133, 89) | 0 (−133, 122) | |
| Basophils | NHANES | cells/µl | 0 (−110, 110) | 0 (−110, 115) | 0 (−110, 108) |
| THLHP | cells/µl | 0 (0, 0) | 0 (0, 0) | 0 (0, 0) | |
| CRP | NHANES | mg/l | 2.49 (1.61, 3.54) | 3.66 (2.81, 4.62) | 2.04 (1.50, 2.66) |
| % | 169.0% (105.9%, 244.7%) | 247.2% (184.6%, 318.0%) | 137.7% (98.0%, 184.2%) | ||
| THLHP | mg/l | 2.45 (0.67, 5.85) | 2.73 (0.95, 5.84) | 0.26 (−0.58, 1.80) | |
| % | 180.7% (46.1%, 436.6%) | 199.3% (65.1%, 447.3%) | 19.1% (−38.2%, 138.8%) |
For each trimester, delta was calculated as the difference from non-pregnant cycling. Estimated median, 5th and 95th percentiles for delta values were estimated as the difference between parameter distributions, with the exception of THLHP monocytes and NHANES and THLHP basophils, which were calculated using the difference between posterior population distributions to include excess zero values.