Fig. 7. Vactosertib restores erectile function in Peyronie's disease (PD) rats. (A) Representative intracavernous pressure (ICP) responses in age-matched controls and PD rats that received Vactosertib (10 mg/kg) or vehicle. Stimulus interval is indicated by the solid bar (1 minute). (B, C) Ratios of the mean maximal ICP/mean systolic blood pressure (MSBP) and total ICP (area under the curve) to MSBP. Each bar depicts the mean value (±standard errors) of n=6 animals per group. ^ap<0.05, compared with the control group; ^bp<0.05, compared with the PD+Vactosertib group.