Table 2.
Characteristics of included studies.
| Study | Drug | Asthma severity | Study design and number of participants | Method of gene identification | Ethnicity (number recruited) | Age range recruited years (mean) |
|---|---|---|---|---|---|---|
| Israel 2004 [29] | Inhaled SABA | Mild asthma | RCT, 78 | Candidate gene | White (56), Black (15), Hispanic (6), Other (11) | 18–55 years |
| Tan 1997 [30] | Inhaled LABA | Moderately severe asthma | RCT, 22 | Candidate gene | Not stated | No mean age given |
| Park 2015 [32] | Oral corticosteroids | Mild to moderate asthma | RCT, 489 | GWAS | Caucasian | 5–12 years |
| Park 2017 [33] | Oral corticosteroids | Mild to moderate asthma | RCT, 461 | GWAS | Caucasian | 5–12 years |
| Hawcutt 2018 [31] | Inhaled ± oral corticosteroids | All severities | Cohort study, 407 | GWAS | Caucasian | 5–18 (11.6) |
RCT randomised controlled trial, GWAS genome wide association study