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. 2020 Sep 15;13(12):100855. doi: 10.1016/j.tranon.2020.100855

Fig. 1.

Fig. 1

Fluorescence in situ hybridization (FISH) analysis of c-MYC, BCL2 and BCL6 gene loci and chromosome 11q aberration in childhood Burkitt lymphoma cases using (A) c-MYC break-apart probes, (B) IGH-MYC probes, (C) additional c-MYC break-apart probes for untypical break-apart of c-MYC loci, (D) 11q aberration probes, (E) BCL2 break-apart probes and (F) BCL6 break-apart probes. Scale bar, 2 μm. c-MYC+, c-MYC break-apart positive; c-MYC-, c-MYC break-apart negative; IGH-MYC+*, IGH-MYC untypical fusion; IGH-MYC-, IGH-MYC fusion negative; c-MYC+*, c-MYC untypical break-apart; 11q23-, 11q23 copy number normal; 11q24.1-, 11q24.1 copy number normal; BCL2-, BCL2 break-apart negative; BCL2+Δ, BCL2 copy number anomaly; BCL6-, BCL6 break-apart negative; BCL6+Δ, BCL6 copy number anomaly.