Table 1.
Model 1a. [Both groups] Predictors of Log10(CE) |
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Variable | Level | Effect(∆lgCE) | SE | P |
OXT Dose* | (ref. = Placebo) | - | - | - |
20 IU* | 0.02 | 0.01 | 0.05 | |
40 IU | 0.02 | 0.01 | 0.08 | |
Group | (ref. = Control) | - | - | - |
PTSD-AUD | 0.02 | 0.03 | 0.47 | |
Age* | 0.00 | 0.00 | >0.01 | |
PTSD-AUD x 20 IU Dose | −0.01 | 0.01 | 0.56 | |
PTSD-AUD x 40 IU Dose | −0.03 | 0.02 | 0.08 | |
Crossover Order | >0.34 | |||
Group x Order | >0.34 | |||
Model 1b.† [Placebo visit only] Predictors of Log10(CE) |
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Variable | Level | Effect(∆lgCE) | SE | P |
OXT Dose | (Placebo only) | - | - | - |
Group* | (ref. = Control) | - | - | - |
PTSD-AUD* | 0.04 | 0.01 | 0.01 | |
Age* | <0.01 | <0.01 | <0.01 | |
Model 1c. [HC only] Predictors of Log10(CE) |
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Variable | Level | Effect(∆lgCE) | SE | P |
Group | (HC only) | - | - | - |
OXT Dose* | (ref. = Placebo) | - | - | - |
20 IU* | 0.02 | 0.01 | 0.04 | |
40 IU | 0.02 | 0.01 | 0.06 | |
Age* | <0.01 | <0.01 | <0.01 | |
Crossover Order | >0.31 | |||
Model 1d. [PTSD-AUD only] Predictors of Log10(CE) |
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Variable | Level | Effect(∆lgCE) | SE | P |
Group | (PTSD-AUD only) | - | - | - |
OXT Dose | (ref. = Placebo) | - | - | - |
20 IU | 0.01 | 0.01 | 0.20 | |
40 IU | −0.01 | 0.01 | 0.51 | |
Age* | <0.01 | <0.01 | <0.01 | |
Crossover Order | > 0.15 |
Abbrev.: CE=congruency effect; Effect = per unit effect size (regression coefficient); ∆lg=change in log units; SE= standard error; OXT= oxytocin; IU= international units; PTSD= posttraumatic stress disorder; AUD= alcohol use disorder. †Post-hoc analysis.