Skip to main content
. Author manuscript; available in PMC: 2021 Oct 1.
Published in final edited form as: Drug Alcohol Depend. 2020 Aug 5;215:108221. doi: 10.1016/j.drugalcdep.2020.108221

Table 2.

Generalized Structural Equation Regression Mixture Model Results of HRQoL

Characteristic Responsive Pharmacotherapy Responsive
Variables β se p-value β se p-value
Shape Parameters
Constant 2.642 0.847 0.002 0.820 0.102 <0.001
Linear Trend −0.055 0.048 0.251 0.018 0.008 0.039
Quadratic Term 0.001 0.004 0.740 −0.001 0.001 0.172
Pharmacotherapy received
Buprenorphine-Naloxone −0.041 0.196 0.835 0.058 0.022 0.009
Extended-Release Naltrexone 0.091 0.180 0.613 0.067 0.022 0.003
Preference for Received Pharmacotherapy
Preferred −0.307 0.167 0.066 −0.021 0.023 0.363
Neutral −0.106 0.234 0.650 0.008 0.021 0.702
Baseline Variables
Intravenous Drug Use −0.188 0.231 0.415 0.013 0.022 0.556
Average Age −0.022 0.008 0.008 0.000 0.001 0.953
Female 0.098 0.131 0.454 −0.009 0.019 0.629
White Race 0.611 0.161 <0.001 −0.026 0.019 0.176
Medicaid 1.323 0.191 <0.001 −0.039 0.019 0.040
High School Education −0.384 0.262 0.143 0.031 0.020 0.115
Married 1.132 0.125 <0.001 −0.066 0.040 0.099
Initial HRQoL Value 0.564 0.195 0.004 0.173 0.063 0.006
Motivation Index −0.449 0.092 <0.001 0.007 0.010 0.469
Addiction Severity Index Measures
Medical −0.063 0.176 0.718 −0.080 0.033 0.015
Employment 0.185 0.196 0.346 −0.069 0.029 0.016
Alcohol −0.244 0.191 0.202 0.004 0.041 0.931
Drug 1.269 0.885 0.152 −0.294 0.105 0.005
Legal 0.662 0.378 0.080 −0.022 0.041 0.586
Family/Social −0.656 0.228 0.004 0.037 0.030 0.229
Psychiatric −0.183 0.038 <0.001 −0.157 0.045 0.001
N (total) 2,622
N(censored) 1,508
N (uncensored) 1,114

HRQoL = Health Related Quality-of-life

Notes: Site fixed effects included in model but not reported in table. Standard errors are clustered at the participant level. Pharmacotherapy received is dichotomous and refers to the past 30 days.