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. Author manuscript; available in PMC: 2021 Sep 1.
Published in final edited form as: Gastroenterology. 2020 May 20;159(3):1036–1050.e8. doi: 10.1053/j.gastro.2020.05.051

Figure 4. Pancreas-specific deletion of CNB1 protects against post-ERCP pancreatitis (PEP).

Figure 4.

(A) Representative H&E images of the pancreas (200X) from the sham and PEP conditions from Cnb1pancf/f and Cnb1PancΔ/Δ mice along with overall histological severity scoring. (B) Edema thresholding by ImageJ. (C) Subscoring for necrosis. (D) Subscoring for inflammatory infiltrate and immunostaining for pancreatic MPO (400X). (E) Serum amylase. n=5 animals per groups; *p<0.05, compared to the controls; #p<0.05, compared to the Cnb1f/f groups.