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. Author manuscript; available in PMC: 2021 Nov 1.
Published in final edited form as: Bone. 2020 Jul 27;140:115547. doi: 10.1016/j.bone.2020.115547

Table 1.

Study population by clinical OI type

All OI types OI-I OI-III OI-IV P
N (m/f) 144 (76/68) 55 (34/21) 28 (12/16) 61 (30/31) 0.20
Age (years) 18.3 (10.7) 19.6 (14.2) 18.5 (6.1) 17.0 (8.3) 0.44
History of Bisphosphonate Treatment (N, %) 114 (79%) 29 (53%) 27 (96%) 58 (95%) <0.001
Height z-score −3.3 (3.0) −0.8 (1.0)b,c −8.0 (1.8)a,c −3.5 (1.7)a,b <0.001
Mean Hand Bone Length z-score −1.1 (1.4) −0.2 (1.0)b,c −2.9 (1.2)a,c −1.2 (1.0)a,b <0.001
Pattern Variability Index 0.46 (0.32) 0.42 (0.32) 0.52 (0.36) 0.47 (0.31) 0.36

Results are shown as N or mean (SD). P values indicate significance of the difference between OI types (ANOVA or chi square tests, as appropriate). Superscripts indicate significant differences (Bonferroni’s adjustment) to

a:

OI type I,

b:

OI type III,

c:

OI type IV.