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. Author manuscript; available in PMC: 2021 Nov 1.
Published in final edited form as: Exp Neurol. 2020 Jul 25;333:113415. doi: 10.1016/j.expneurol.2020.113415

Figure 4. Impact of MCT1 deficiency on sensory behavioral testing after diabetes induction.

Figure 4.

Paw withdrawal frequency to mechanical stimulation by calibrated von Frey monofilaments of forces 0.07 g (A) and 0.45 g (B) and paw withdrawal latency (C) to thermal stimulation by radiant paw-heating assay in Het MCT1-null mice and Wild-type littermates before and after STZ administration with hyperglycemia, n = 6–13 per group. Paw withdrawal frequency to mechanical stimulation by calibrated von Frey monofilaments of forces 0.07 g (D) and 0.45 g (E) and paw withdrawal latency (F) to thermal stimulation by radiant paw-heating assay in Het MCT1-null mice and Wild-type littermates before and after STZ administration without hyperglycemia, n = 5-8 per group. Current set at baseline level: 20%, 10–12 s; cut off time; 30 s. Mean ± SEM, *p < 0.05; **p <0 .01; ***p <0 .001; ****p <0 .0001, two-way ANOVA with Bonferroni's multiple comparisons test. N1 Glucose, STZ administration without hyperglycemia