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. Author manuscript; available in PMC: 2021 Sep 17.
Published in final edited form as: Cell Chem Biol. 2020 May 12;27(9):1130–1139.e4. doi: 10.1016/j.chembiol.2020.04.009

Fig. 6. Working model for plasma protein regulation of PM20D1 and N-acyl amino acids.

Fig. 6.

Lipoprotein association functions to co-activate PM20D1 activity, which then synthesizes N-acyl amino acids. These lipids then circulate in an inactive albumin-bound as well as a biologically active free form. Only free N-acyl amino acids can stimulate cellular respiration.