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. Author manuscript; available in PMC: 2021 Oct 1.
Published in final edited form as: Arch Toxicol. 2020 Jul 16;94(10):3515–3526. doi: 10.1007/s00204-020-02844-w

Figure 5. Effects of METH self-administration on cleavage of caspases-9 and −6 in the dorsal striatum.

Figure 5.

Representative western blot bands and corresponding quantitative analysis of the initiator caspase, cleaved caspase-9 (A) and effector, caspase-6 (B). SS rats showed significant decreases in cleaved caspase −9 (p < 0.001) and caspase-6 (p < 0.01) in comparison to SR rats. (C) There were no changes in caspase-3 cleavage in any of the group. α-tubulin was used for normalization. Key to statistics: ** p<0.01 vs. CT; $, $ $ p<0.05, p<0.01 vs. YSR, respectively; ##, ### p<0.01, p<0.001 vs. SR, respectively; ^ p<0.05 vs. YSS.