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. Author manuscript; available in PMC: 2021 Jan 13.
Published in final edited form as: Lab Invest. 2020 Jul 13;100(10):1367–1383. doi: 10.1038/s41374-020-0463-y

Table 5:

Performance of DELINEATE Steatosis Pixel% (DSP%), DELINEATE Steatosis Count% (DSC%), and Aperio Steatosis Pixel%, (ASP%) for differentiation of patient groups of steatosis grades by pathologist assessment.

Steatosis Measure  Steatosis Grade
 0 vs 1–3  0–1 vs 2–3  0–2 vs 3
 DSP%  Threshold  1.26  7.34  11.91
 AUROC (95% CI)  0.992 (0.971–1.00)  0.977 (0.938–1.00)  0.930 (0.851–1.00)
 Sensitivity  96.80%  91.30%  92.30%
 Specificity  100%  100%  82.60%
 Accuracy  97%  94%  86%
 DSC%  Threshold  0.0004145  0.0018375  0.002755
 AUROC (95% CI)  0.977 (0.928–1.00)  0.990 (0.970–1.00)  0.983 (0.954–1.00)
 Sensitivity  96.80%  91.30%  100%
 Specificity  100%  100%  91.30%
 Accuracy  97%  94%  94%
 ASP%  Threshold  7.45  11.89  13.48
 AUROC (95% CI)  0.922 (0.819–1.00)  0.957 (0.883–1.00)  0.946 (0.880–1.00)
 Sensitivity  81.25%  91.30%  100%
 Specificity  100%  100%  78.20%
 Accuracy  83%  94%  86%