Extended Data Fig. 7.

Csf2rb^−/− Ldlr^−/− mice fed HFD for 12 days Csf2rb^+/− Ldlr^−/− or Csf2rb^−/− Ldlr^−/− mice were fed HFD for 12 days to induce atherosclerotic lesions in the aortic arch. Aorta were stained for MHC II (red) and imaged by tile scanning whole mount confocal microscopy for macrophage burden and morphologic changes associated with foamy cell development. Three representative images (n=7 for Csf2rb^+/− Ldlr^−/−) or (n=4 Csf2rb^−/− Ldlr^−/−) were selected from a single experiment.