Table 1. Basic information of LAA cerebrovascular disease, age-related CSVD and control groups.
| Basic information1 | LAA (n=20) | Age-related CSVD (n=20) | Control (n=14) | Fabry disease (n=10) | p3 |
|---|---|---|---|---|---|
| Age, years | 62.9 ± 11.7 | 62.4 ± 10.7 | 64.8 ± 13.7 | 43.7 ± 16.2 | 0.001 |
| Gender | 0.151 | ||||
| Male, N (%) | 15 (75) | 16 (80) | 7 (50) | 5 (50) | |
| Female, N (%) | 5 (25) | 4 (20) | 7 (50) | 5 (50) | |
| Hypertension, N (%) | 17 (85) | 15 (75) | 8 (57) | 4 (40) | 0.061 |
| Diabetes, N (%) | 11 (55) | 8 (40) | 3 (21) | 1 (10) | 0.061 |
| Smoking, N (%) | 10 (50) | 11 (55) | 4 (29) | 2 (20) | 0.188 |
| BMI, kg/m2 | 24.71 (23.24–27.60) | 24.22 (21.53–27.10) | 25.53 (23.33–27.75) | 21.37(18.08–25.34) | 0.132 |
| TG, mmol/l | 1.24 (0.96–1.58) | 1.46 (0.96–1.92) | 1.36 (0.98–1.84) | 1.53 (0.73–2.28) | 0.901 |
| TC, mmol/l | 3.68 ± 0.97 | 3.87 ± 1.04 | 4.36 ± 1.02 | 4.35 ± 1.18 | 0.187 |
| LDL, mmol/l | 2.12 ± 0.72 | 2.29 ± 0.85 | 2.60 ± 0.75 | 2.65 ± 1.03 | 0.243 |
| HDL, mmol/l | 0.93 (0.82–1.04) | 0.88 (0.80–1.03) | 1.11 (0.88–1.31) | 1.16 (0.92–1.31) | 0.091 |
| HCY, mmol/l | 12.84 (10.99–19.33) | 13.26 (10.62–17.25) | 13.04 (8.96–16.06) | / | 0.717 |
| Combination with severe WMH2, N (%) | 5 (25%) | 5 (25%) | 0 | / | 0.106 |
| ARWMC | 5 (2–11) | 7 (3–12) | 3 (1-4) | / | 0.095 |
1Continuous variables were described as mean±SD (normal distribution) or median (IQR)(non-normal distribution), Categorical variables were described as frequency (percentage);
2severe WMH was defined as ARWMC>10;
3Continuous variables were analyzed by one-way ANOVA if normally distributed, and by non-parametric test if not. Categorical variables were analyzed by chi-square test. P<0.05 was considered to be statistically different.