Table 3.
The 50 most differentially expressed genes between Dip2b+/+ vs Dip2b−/− (Fold change ≥ 2, FDR < 0.01).
| Up-regulated genes | FC ≥ 2 | FDR | P value | Down-regulated genes | FC < 2 | FDR | P value |
|---|---|---|---|---|---|---|---|
| Ear1 | 13.11374217 | 0 | 0 | Pax8 | −10.82813648 | 2.23E-12 | 4.84E-13 |
| Ear10 | 11.05934446 | 5.87E-53 | 4.20E-54 | Pax2 | −10.60316268 | 6.36E-13 | 1.34E-13 |
| Ear2 | 10.37424254 | 0 | 0 | Havcr1 | −10.48850965 | 1.70E-104 | 6.57E-106 |
| Fpr2 | 10.35974956 | 7.82E-95 | 3.25E-96 | Sprr2f | −10.46147945 | 1.11E-46 | 8.74E-48 |
| Eno1b | 9.370435927 | 0 | 0 | Hoxa10 | −10.24317398 | 1.20E-302 | 1.60E-304 |
| Ndufa11b | 8.939579214 | 7.79E-15 | 1.50E-15 | Hoxa11 | −10.05799172 | 1.94E-139 | 5.62E-141 |
| Entpd4 | 8.569855608 | 2.50E-65 | 1.47E-66 | Hoxd10 | −9.920352855 | 2.22E-108 | 8.23E-110 |
| Sell | 8.22881869 | 3.05E-38 | 2.83E-39 | ccdc198 | −9.840777924 | 6.09E-61 | 3.81E-62 |
| Zfp967 | 8.184875343 | 6.81E-36 | 6.67E-37 | Hmga1b | −9.63828506 | 0 | 0 |
| Hamp2 | 8.159871337 | 9.74E-07 | 3.02E-07 | Hoxc10 | −9.564784619 | 1.18E-245 | 1.93E-247 |
| Wfdc21 | 8.06608919 | 1.89E-06 | 5.98E-07 | Tff1 | −9.398743692 | 2.19E-17 | 3.80E-18 |
| Stfa1 | 8.027905997 | 7.06E-06 | 2.34E-06 | Hoxc8 | −9.221587121 | 1.08E-80 | 5.25E-82 |
| Hist2h3c1 | 7.768184325 | 6.95E-08 | 1.97E-08 | Hoxc9 | −9.204571144 | 1.32E-57 | 8.74E-59 |
| Gm14296 | 7.491853096 | 5.23E-40 | 4.70E-41 | Hist2h3c2 | −9.022367813 | 2.75E-18 | 4.60E-19 |
| Hist2h2aa2 | 7 | 3.55E-04 | 1.41E-04 | Clca1 | −8.854868383 | 1.19E-77 | 5.97E-79 |
| Adora3 | 6.845490051 | 2.05E-15 | 3.83E-16 | Reg1 | −8.764871591 | 1.38E-18 | 2.28E-19 |
| Evi2 | 6.584962501 | 1.53E-21 | 2.27E-22 | Tff2 | −8.717676423 | 3.48E-13 | 7.19E-14 |
| Mstn | 6.584962501 | 7.79E-15 | 1.50E-15 | Cyp4a12b | −8.632995197 | 2.87E-54 | 2.01E-55 |
| Gm39743 | 6.539158811 | 1.75E-10 | 4.22E-11 | Spaca7 | −8.581200582 | 8.74E-17 | 1.55E-17 |
| Ang5 | 6.539158811 | 6.80E-04 | 2.79E-04 | Hoxd11 | −8.558420713 | 1.49E-85 | 6.78E-87 |
| Ly6k | 6.491853096 | 3.55E-04 | 1.41E-04 | Gsta1 | −8.471675214 | 4.37E-17 | 7.67E-18 |
| Bmx | 6.459431619 | 3.99E-15 | 7.58E-16 | Pkp1 | −8.438791853 | 2.82E-91 | 1.21E-92 |
| Cd177 | 6.459431619 | 1.14E-13 | 2.31E-14 | Hist1h4m | −8.361943774 | 3.12E-07 | 9.29E-08 |
| Lipf | 6.303780748 | 3.65E-06 | 1.18E-06 | Gm14434 | −8.290018847 | 1.33E-81 | 6.36E-83 |
| Gm14548 | 6.28128611 | 9.11E-75 | 4.75E-76 | Hoxd9 | −8.162391329 | 1.74E-66 | 1.01E-67 |
| Gm46223 | 6.247927513 | 4.88E-09 | 1.28E-09 | Klhl1 | −8.154818109 | 2.26E-64 | 1.35E-65 |
| LOC100041057 | 6.209453366 | 3.65E-06 | 1.18E-06 | Clca3b | −8.142107057 | 6.44E-105 | 2.47E-106 |
| Ear6 | 6.189824559 | 3.90E-21 | 5.85E-22 | Spink8 | −8.06608919 | 3.34E-10 | 8.17E-11 |
| DXBay18 | 6.169925001 | 1.22E-11 | 2.75E-12 | Clec18a | −8.033423002 | 7.99E-54 | 5.63E-55 |
| Ms4a8a | 6.161887682 | 5.48E-20 | 8.53E-21 | Gm8210 | −7.990827547 | 0 | 0 |
| Gm44805 | 6.14974712 | 0.008947464 | 0.00428538 | Il24 | −7.948367232 | 1.39E-15 | 2.59E-16 |
| Tex45 | 6.132713922 | 3.28E-33 | 3.39E-34 | Prr32 | −7.77478706 | 8.75E-14 | 1.76E-14 |
| Serpinb10 | 6.125843933 | 2.50E-68 | 1.40E-69 | Malrd1 | −7.768184325 | 6.05E-85 | 2.77E-86 |
| Cyp4f18 | 6.076815597 | 7.19E-25 | 9.49E-26 | Gc | −7.707359132 | 1.36E-21 | 2.00E-22 |
| A530032D15Rik | 6.044394119 | 3.55E-04 | 1.41E-04 | Dmbt1 | −7.693486957 | 6.44E-75 | 3.35E-76 |
| LOC677525 | 6.044394119 | 3.55E-04 | 1.41E-04 | Apela | −7.607330314 | 8.46E-11 | 2.00E-11 |
| Sod3 | 6.042856338 | 0 | 0 | Hist1h3c | −7.54689446 | 7.07E-05 | 2.58E-05 |
| F13a1 | 6.005624549 | 0 | 0 | Hoxd4 | −7.459431619 | 8.27E-26 | 1.06E-26 |
| Prss16 | 5.930737338 | 1.34E-07 | 3.89E-08 | Pmp2 | −7.434628228 | 1.75E-13 | 3.56E-14 |
| Awat1 | 5.906890596 | 5.07E-05 | 1.82E-05 | Gsdmc2 | −7.400879436 | 4.25E-23 | 5.94E-24 |
| Gm36504 | 5.882643049 | 9.74E-07 | 3.02E-07 | Pitx2 | −7.309855263 | 2.70E-43 | 2.26E-44 |
| Rnase2b | 5.832890014 | 0.008942223 | 0.00428538 | Kcnj16 | −7.235216462 | 2.60E-183 | 5.72E-185 |
| 2010005H15Rik | 5.817623258 | 1.43E-22 | 2.04E-23 | Scin | −7.192292814 | 6.79E-193 | 1.41E-194 |
| Gm5796 | 5.754887502 | 1.36E-05 | 4.64E-06 | Dcdc2a | −7.144266046 | 0 | 0 |
| Gm9733 | 5.754887502 | 0.008949561 | 0.00428538 | Dclk3 | −7.14068778 | 5.49E-243 | 9.12E-245 |
| Gpr15 | 5.727920455 | 3.55E-04 | 1.41E-04 | Spns3 | −7.108524457 | 3.34E-10 | 8.17E-11 |
| Fhl5 | 5.700439718 | 0.002477977 | 0.001093626 | Dnajc19-ps | −7.098032083 | 2.70E-04 | 1.06E-04 |
| Klrb1b | 5.700439718 | 9.74E-07 | 3.02E-07 | Hoxd8 | −7.096275911 | 1.84E-82 | 8.73E-84 |
| Mcemp1 | 5.698247727 | 1.99E-110 | 7.28E-112 | Lhx1 | −7.055282436 | 5.42E-21 | 8.18E-22 |
| Sftpa1 | 5.672425342 | 6.37E-29 | 7.41E-30 | Cltrn | −7.044394119 | 1.32E-09 | 3.34E-10 |