Table 3.
Demographic and clinical characteristics of the adult PLB patients.
| Characteristic | Number | Percentage | |
|---|---|---|---|
| Sex | |||
| Female | 1251 | 48.9% | |
| Male | 1307 | 51.1% | |
| Marital status | |||
| Unmarried | 1152 | 45.2% | |
| Married | 1403 | 54.8% | |
| Age | |||
| 20–40 | 462 | 18.1% | |
| 40–60 | 674 | 26.3% | |
| 60–80 | 1021 | 39.9% | |
| 80– | 401 | 15.7% | |
| Race | |||
| White | 2189 | 85.6% | |
| Black | 206 | 8.1% | |
| American Indian/Alaska native | 23 | 0.9% | |
| Asian or Pacific Islander | 140 | 5.5% | |
| Lymphoma type | |||
| Hodgkin lymphoma | 24 | 0.9% | |
| Non-Hodgkin lymphoma | 2534 | 99.1% | |
| Primary site | |||
| Axial | 1430 | 55.9% | |
| Appendicular | 905 | 35.4% | |
| Craniofacial | 223 | 8.7% | |
| Laterality | |||
| Bilateral, single primary | 32 | 1.3% | |
| Left: origin of primary | 607 | 23.7% | |
| Right: origin of primary | 555 | 21.7% | |
| Not a paired site | 1364 | 53.3% | |
| Histologic type: broad groupings | |||
| ICD-O-3:9590-9599 | Malignant lymphomas, NOS or diffuse | 367 | 14.3% |
| ICD-O-3:9650-9669 | Hodgkin lymphomas | 24 | 0.9% |
| ICD-O-3;9670-9699 | NHL– mature B-cell lymphomas | 2082 | 81.4% |
| ICD-O-3:9700-9719 | NHL–mature T- and NK-cell lymphomas | 56 | 2.2% |
| ICD-O-3:9720-9729 | NHL-precursor-cell lymphoblastic lymphoma | 29 | 1.1% |
| Ann Arbor stage | |||
| Stage I | 1367 | 53.4% | |
| Stage II | 285 | 11.1% | |
| Stage III | 58 | 2.3% | |
| Stage IV | 848 | 33.2% | |
| Number of bone lesions | |||
| Single | 2328 | 91.0% | |
| Multiple (⩾2) | 230 | 9.0% | |
| Radiation sequence with surgery | |||
| No radiation and/or cancer-directed surgery | 2202 | 86.1% | |
| Radiation after surgery | 339 | 13.3% | |
| Radiation prior to surgery | 12 | 0.5% | |
| Radiation before and after surgery | 5 | 0.2% | |
| Surgery | |||
| No | 1940 | 75.8% | |
| Yes | 618 | 24.2% | |
| Radiation | |||
| No | 1167 | 45.6% | |
| Yes | 1391 | 54.4% | |
| Chemotherapy | |||
| No | 617 | 24.1% | |
| Yes | 1941 | 75.9% | |
| Overall survival | |||
| Censored | 1440 | 56.3% | |
| Dead | 1118 | 43.7% | |
| Disease-specific survival | |||
| Censored | 1833 | 71.7% | |
| Dead | 725 | 28.3% | |
| Year of diagnosis | |||
| 1975–1986 | 111 | 4.3% | |
| 1986–1996 | 340 | 13.3% | |
| 1996–2006 | 890 | 34.8% | |
| 2006–2016 | 1217 | 47.6% | |
ICD, International Classification of Diseases; NHL, non-Hodgkin lymphoma; NK, natural killer (cell); NOS, not otherwise specified; PLB, primary lymphoma of bone.