Table 2.
Variable | Value | Relapse |
Relapse free survival |
|||
---|---|---|---|---|---|---|
No | Yes | p | HR (95% CI) | p | ||
AR (%) | 80 (60−90) | 70 (12.5−80) | 0.011 | 0.99 (0.99−1) | 0.025 | |
<80% | 52 (53.06%) | 46 (46.94%) | 0.002 | Baseline | ||
⩾80% | 81 (73.64%) | 29 (26.36%) | 0.53 (0.34−0.85) | 0.008 | ||
ER (%) | 80 (70−80) | 70 (60−80) | 0.038 | 0.99 (0.98−1) | 0.068 | |
<80% | 54 (40.6%) | 41 (54.67%) | 0.060 | Baseline | ||
⩾80% | 79 (59.4%) | 34 (45.33%) | 0.69 (0.44−1.09) | 0.116 | ||
AR/ER ratio | 1 (0.8−1.12) | 0.89 (0.29−1.12) | 0.281 | 1.06 (0.88−1.27) | 0.536 | |
<2 | 125 (64.77%) | 68 (35.23%) | 0.410 | Baseline | ||
⩾2 | 8 (53.33%) | 7 (47.67%) | 1.47 (0.67−3.20) | 0.334 | ||
Grade | G1 − G2 | 97 (65.54%) | 51 (34.46%) | 0.524 | Baseline | |
G3 | 36 (60%) | 24 (40%) | 1.24 (0.76−2.01) | 0.394 | ||
Stage | I | 76 (81.72%) | 17 (18.28%) | 1 | Baseline | |
yI | 6 (85.71%) | 1 (14.29%) | 0.89 (0.12−6.77) | 0.912 | ||
II | 32 (55.17%) | 26 (44.83%) | 1 | Baseline | ||
yII | 8 (53.33%) | 7 (46.67%) | 0.79 (0.34−1.83) | 0.581 | ||
III | 10 (50%) | 10 (50%) | 0.022 | Baseline | ||
yIII | 1 (7.69%) | 12 (92.31%) | 1.46 (0.6−3.52) | 0.405 | ||
Vascular invasion | Absent | 64 (77.11%) | 19 (22.89%) | 0.061 | Baseline | |
Mild | 42 (61.76%) | 26 (38.24%) | 1.80 (1−3.26) | 0.051 | ||
Diffuse | 7 (53.85%) | 6 (46.15%) | 2.23 (0.89−5.6) | 0.086 | ||
Histotype | NOS/ductal | 87 (66.41%) | 44 (33.59%) | 0.485 | Baseline | |
Lobular | 39 (58.21%) | 28 (41.79%) | 1.13 (0.7−1.81) | 0.620 | ||
Other | 7 (70.00%) | 3 (30.00%) | 0.89 (0.28−2.88) | 0.850 | ||
ki67 | <20% | 103 (69.59%) | 45 (30.41%) | 0.011 | Baseline | |
⩾20% | 30 (50%) | 30 (50%) | 2.3 (1.44−3.66) | <0.001 |
AR, androgen receptor; baseline, intercept of the regression; CI, 95% confidence interval; ER, estrogen receptor; HR, hazard ratio; NOS, not otherwise specified; p = unadjusted p-value from Wilcoxon rank sum test, Chi-square test, or Fisher’s exact test as appropriate; value, value that the variable assumes; variable, analyzed variable; yI – yII – yIII, patients who performed neoadjuvant treatment.