Figure 2.

Schematic representation of the different types of nanoparticles used for the development of new therapeutic approaches and vaccination of systemic fungal infections. Polymeric nanoparticles: Nanocapsules contain an open core with drug space, surrounded by a polymeric membrane. The nanospheres carry the drugs evenly distributed over a polymeric matrix. NLC (Nanostructured lipid carriers): Structure composed of a solid lipid and liquid lipid fraction into which the drug may be incorporated within the structure. Liposomes: Nanoparticle with unilamellar or multilamellar structure with space for drug transport between layers and/or core. Dendrimers: Complex structure branched and highly organized around the nucleus, the drug can be incorporated between the layers or on the surface of the structure. Nanoemulsion: Colloidal dispersion composed of an oil and water phase that promotes drug encapsulation. Metallic nanoparticle: Nanoparticle of metal core and intrinsic antimicrobial activity. Magnetic nanoparticle: Nanoparticle of metal core with magnetic properties.