Table 1. Demographic and clinical characteristics in patients treated with bromhexine-hydrochloride and standard group .
| Standard group (n=39) | Treatment group (n=39) | P value | |
| Demographic characteristics | |||
| Age(year) | 61.1 ±16.1 | 58.4±13.7 | 0.43a |
| Gender (male/female) | 24/15 | 19/20 | 0.255b |
| BMI (kg/m2) | 27.8±4.3 | 27.6±4.4 | 0.812a |
| Diabetes mellitus, No. (%) | 10 (25.6%) | 16 (41.0%) | 0.150b |
| Hypertension, No. (%) | 20 (51.3%) | 19 (48.7%) | 0.821 |
| Baseline clinical characteristics | |||
| APACHE Score | 10.2±4.6 | 9.3 ±2.9 | 0.295a |
| Time-lag of symptom initiation to hospital admission (days) | 8.3±5.8 | 7.7±4.1 | 0.632 |
| SpO2 (%) | 88.5±4.4 | 87.8±4.6 | 0.550a |
| Fever, No. (%) | 18 (46.2%) | 19 (48.7%) | 0.821b |
| Cough, No. (%) | 26 (66.7%) | 30 (76.9%) | 0.314b |
| Dyspnea, No. (%) | 28 (71.8%) | 26 (66.7%) | 0.624b |
| Lassitude, No. (%) | 24 (61.5%) | 18 (46.2%) | 0.173b |
| Myalgia, No. (%) | 27 (69.2%) | 17 (43.6%) | 0.022b |
| Headache, No. (%) | 11 (28.2%) | 7 (17.9%) | 0.282b |
| GI symptoms, No. (%) | 13 (33.3%) | 16 (41.0%) | 0.482b |
| NLR (IQR) | 5.5 (8.1) | 4.7 (4.2) | 0.526c |
| Positive CRP, No. (%) | 33 (91.7%) | 29 (87.9%) | 0.450d |
| LDH U/L | 470.0 (262.5) | 507.0 (177.0) | 0.742c |
Abbreviations: APACHE, acute physiology and chronic health evaluation; Spo2, saturation of peripheral oxygen; GI, Gastrointestinal; NLR, neutrophil lymphocyte ratio; CRP, C-reactive protein; LDH, lactate dehydrogenase; ICU, intensive care unit.
aIndependent samples t test; bChi-squared test; cCalculated with Mann-Whitney; dFisher's exact test
The values shown were based on total number of patients who contributed values.