Table 2. Post-treatment clinical characteristics in patients treated with bromhexine and standard group .
| Demographic characteristics | Standard group (n=39) | Treatment group (n=39) | P value |
| Primary outcomes | |||
| Mortality, No. (%) | 5 (12.8) | 0 (0) | 0.027d |
| ICU admission, No. (%) | 11 (28.2) | 2 (5.1) | 0.006b |
| Mechanical ventilation, No. (%) | 9 (23.1) | 1 (2.6) | 0.007b |
| Secondary outcomes | |||
| Fever, No. (%) | 3 (10.0) | 0 (0) | 0.125d |
| Cough, No. (%) | 12 (40.0) | 2 (6.9) | 0.003b |
| Dyspnea, No. (%) | 14 (48.3) | 1 (3.4) | <0.001b |
| Lassitude, No. (%) | 10 (34.5) | 2 (6.9) | 0.010b |
| Myalgia, No. (%) | 4 (13.8) | 3 (10.3) | 0.500d |
| Headache, No. (%) | 3 (10.0) | 0 (0) | 0.125d |
| GI symptoms, No. (%) | 1 (3.3) | 4 (13.8) | 0.166d |
| NLR (IQR) | 3.0 (6.3) | 1.7 (1.0) | 0.052c |
| Positive CRP, No. (%) | 9 (81.8) | 0 (0) | <0.001d |
| LDH U/L mean ±SD | 445.3±115.2 | 363.2±83.6 | 0.056a |
| Hospital stay (days), mean ±SD | 8.1 ±5.5 | 7.6 ±3.5 | 0.587a |
Abbreviations: APACHE, acute physiology and chronic health evaluation; Spo2, saturation of peripheral oxygen; GI, Gastrointestinal; NLR, neutrophil-lymphocyte ratio; IQR, interquartile range; CRP, C-reactive protein; LDH, lactate dehydrogenase; ICU, intensive care unit.
aIndependent Samples t-test; b Chi-squared test; dFisher's exact test, dCalculated with Mann-Whitney;
The values shown were based on the total number of patients who contributed values.