Table 5.

MiRNAs involved in osteoblast regulation.

MiRNA	Relative Expression	Role	Target	References
MiR-140-3p	Upregulation	Regulates osteoblast differentiation	TGFβ3	[92]
MiR-133a-5p	Upregulation	Lowers the expression of osteoblast differentiation markers	Runx2	[93]
MiR-92a-1-5p	Upregulation	Negatively regulates osteogenic differentiation of MC3T3-E1	β-catenin	[94]
MiR-542-3p	Upregulation	Inhibits osteoblast differentiation	BMP-7	[95]
MiR-23b	Upregulation	Promotes osteogenic differentiation in MC3T3-E1 cells	Smad 3	[96]
MiR-15b	Upregulation	Promotes osteoblast differentiation	Crim1, Smurf1, Smad7, and HDAC4	[97]
MiR-29b	Upregulation	Promotes osteoblast differentiation of MC3T3-E1	TGFβ3, HDAC4,	[98]
MiR-375-3p	Upregulation	Inhibits osteogenesis in MC3T3-E1	LRP5 and β-catenin	[99]