Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Hypothetical function of miR-181a/b-1 as rheostat for TCR signaling during selection. (A) How miR-181 affects conventional T cells: Due to their broad affinity window, the effect of the shift in TCR signal strength on selection is relatively small. (B) How miR-181 affects agonist selected T cells: Due to their high and narrow affinity window, the effect of the shift in TCR signal strength on selection is evident.
