4-PBA | 4-Phenylbutyrate |
AD | Alzheimer’s disease |
ADAM10 | A disintegrin and metalloprotease domain 10 |
ALS | Amyloid lateral sclerosis |
AMPAR | AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) receptor |
APP | Amyloid β-precursor protein |
ASK1 | Apoptotic-signaling kinase-1 |
ATF4 | Activating transcription factor 4 |
ATF6 | Activating transcription factor 6 |
ATG | AuTophaGy(ATG)-related proteins |
Aβ | Amyloid-β |
BACE1 | β-APP cleaving enzyme 1 |
BECN1 | Beclin-1 |
BiX | BIP/GRP78 inducer X |
BSE | Bovine spongiform encephalopathy |
C9orf72 | Chromosome 9 open reading frame 72 |
CaBP-9k | Calbindin-D9K |
Ca2+ | Calcium |
CHOP | C/EBPα-homologous protein |
CJD | Creutzfeldt–Jakob disease |
CNS | Central nervous system |
COPII | Coat protein complex II |
CRAC | Ca2+-release-activated Ca2+ |
CREBH | Cyclic adenosine monophosphate (cAMP)-responsive element-binding protein H |
CWD | Chronic wasting disease |
DAPK1 | Death-associated kinase 1 |
eIF2α | Eukaryotic translation initiation factor α |
ER | Endoplasmic reticulum |
ERAD | ER-associated degradation |
ERK | Extracellular signal-regulated kinase |
ERMES | ER-mitochondria encounter structures |
ERp | ER protein |
FoxO1 | Forkhead box protein O1 |
FTD | Frontotemporal dementia |
FUS | Fused in sarcoma |
GADD34 | Growth arrest and DNA-damage-inducible 34 |
GCN2 | General control nonderepressible 2 |
GRP17 | Glycine rich protein 17 |
GRP78 | 78 KDa glucose-regulated protein |
GSK-3β | Glycogen Synthase Kinase 3β |
HD | Huntington disease |
Herp | Homocysteine-inducible ER stress protein |
HIPK2 | Homeodomain interacting protein kinase 2 |
HRD1 | HMG-CoA reductase degradation protein 1 |
HRI | Heme-regulated inhibitor |
Hsp | Heat shock proteins |
IBTs | 2-phenylimidazo[2,1-b]benzothiazole |
IFN-γ | Interferon-gamma |
IKK | IκB kinase |
IL | Interleukin |
IP3R | IP3 receptor |
iPSCs | Induced pluripotent stem cells |
IRE | Inositol-requiring transmembrane kinase/endoribonuclease |
ISRIB | Integrated stress response inhibitor |
JAK/STAT JNK |
Janus kinase/signal transducers and activators of transcription Jun-N-terminal kinase |
KIRA | Kinase inhibiting RNase attenuators |
LBs | Lewy bodies |
LNs | Lewy neurites |
LRRK2 | Leucine-rich repeat kinase 2 |
MAM | Mitochondria-associated ER membrane |
MAP1LC3B | Microtubule associated protein 1 light chain 3 beta |
Mfn2 | Mitochondrial fusion protein mitofusin 2 |
NE | Nuclear envelope |
NF-κB | Nuclear factor-κB |
NINDS | National Institute of Neurological Disorders and Stroke |
NMDA-Rs | N-methyl-d-aspartate receptors |
Osh | Oxysterol-binding homology |
p38 MAPK | p38 mitogen-activated protein kinase |
PARK | Parkinson’s disease protein |
PC12 | Pheochromocytoma of the rat adrenal medulla |
PD | Parkinson’s disease |
PDI | Protein disulfide isomerase |
PE | Phosphatidylethanolamine |
PERK | PKR-like ER kinase |
PI3K/AKT PI4P |
Phosphoinositide 3-kinase/ Protein kinase B Phosphatidylinositol 4-phosphate |
PINK1 | PTEN-induced putative kinase 1 |
PM | Plasma membrane |
PMDs | Protein misfolding disorders |
Pp1 | Protein phosphatase 1 |
PRKN | Parkin |
PrP | Prion protein |
PS | Phosphatidylserine |
PS1/2 | Presenilin-1/2 (PS1/2) |
PTSD | Post-traumatic stress disorder |
RAB1 | Ras-associated binding 1 |
RIDD | Regulated IRE1-dependent decay |
ROS | Reactive oxygen species |
RTK | Receptor tyrosine kinase |
S1P | Site 1 protease |
S2P | Site 2 protease |
SERCA | Sarco/endoplasmic reticulum Ca2+-ATPase |
Sigr1 | Sigma-1 receptor |
SNCA | Synuclein Alpha gene |
SNpc | Substantia nigra pars compacta |
SNPs | Single nucleotide polymorphisms |
SOCE | Store operated Ca2+ entry |
SOD1 | Superoxide dismutase1 |
STIM | Stromal-interacting molecule |
TARDBP or TDP-43 | TAR DNA-binding protein |
TNF | Tumor necrosis factor |
TRAF2 | TNF receptor-associated factor 2 |
TSE | Transmissible spongiform encephalopathies |
TUDCA | Tauroursodeoxycholic acid |
uORF | Upstream open reading frame |
UPR | Unfolded protein response |
VAP VAPB |
Vesicle-associated membrane protein-associated protein Vesicle-associated membrane protein-associated protein B |
VDAC1 | Voltage-dependent anion selective channel protein 1 |
VMP1 | Vacuole membrane protein 1 |
WT | Wild type |
XBP1 | X-box binding protein 1 |
α-SYN | α-synuclein |