Skip to main content
. 2020 Aug 25;21(17):6127. doi: 10.3390/ijms21176127
4-PBA 4-Phenylbutyrate
AD Alzheimer’s disease
ADAM10 A disintegrin and metalloprotease domain 10
ALS Amyloid lateral sclerosis
AMPAR AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) receptor
APP Amyloid β-precursor protein
ASK1 Apoptotic-signaling kinase-1
ATF4 Activating transcription factor 4
ATF6 Activating transcription factor 6
ATG AuTophaGy(ATG)-related proteins
Amyloid-β
BACE1 β-APP cleaving enzyme 1
BECN1 Beclin-1
BiX BIP/GRP78 inducer X
BSE Bovine spongiform encephalopathy
C9orf72 Chromosome 9 open reading frame 72
CaBP-9k Calbindin-D9K
Ca2+ Calcium
CHOP C/EBPα-homologous protein
CJD Creutzfeldt–Jakob disease
CNS Central nervous system
COPII Coat protein complex II
CRAC Ca2+-release-activated Ca2+
CREBH Cyclic adenosine monophosphate (cAMP)-responsive element-binding protein H
CWD Chronic wasting disease
DAPK1 Death-associated kinase 1
eIF2α Eukaryotic translation initiation factor α
ER Endoplasmic reticulum
ERAD ER-associated degradation
ERK Extracellular signal-regulated kinase
ERMES ER-mitochondria encounter structures
ERp ER protein
FoxO1 Forkhead box protein O1
FTD Frontotemporal dementia
FUS Fused in sarcoma
GADD34 Growth arrest and DNA-damage-inducible 34
GCN2 General control nonderepressible 2
GRP17 Glycine rich protein 17
GRP78 78 KDa glucose-regulated protein
GSK-3β Glycogen Synthase Kinase 3β
HD Huntington disease
Herp Homocysteine-inducible ER stress protein
HIPK2 Homeodomain interacting protein kinase 2
HRD1 HMG-CoA reductase degradation protein 1
HRI Heme-regulated inhibitor
Hsp Heat shock proteins
IBTs 2-phenylimidazo[2,1-b]benzothiazole
IFN-γ Interferon-gamma
IKK IκB kinase
IL Interleukin
IP3R IP3 receptor
iPSCs Induced pluripotent stem cells
IRE Inositol-requiring transmembrane kinase/endoribonuclease
ISRIB Integrated stress response inhibitor
JAK/STAT
JNK
Janus kinase/signal transducers and activators of transcription
Jun-N-terminal kinase
KIRA Kinase inhibiting RNase attenuators
LBs Lewy bodies
LNs Lewy neurites
LRRK2 Leucine-rich repeat kinase 2
MAM Mitochondria-associated ER membrane
MAP1LC3B Microtubule associated protein 1 light chain 3 beta
Mfn2 Mitochondrial fusion protein mitofusin 2
NE Nuclear envelope
NF-κB Nuclear factor-κB
NINDS National Institute of Neurological Disorders and Stroke
NMDA-Rs N-methyl-d-aspartate receptors
Osh Oxysterol-binding homology
p38 MAPK p38 mitogen-activated protein kinase
PARK Parkinson’s disease protein
PC12 Pheochromocytoma of the rat adrenal medulla
PD Parkinson’s disease
PDI Protein disulfide isomerase
PE Phosphatidylethanolamine
PERK PKR-like ER kinase
PI3K/AKT
PI4P
Phosphoinositide 3-kinase/ Protein kinase B
Phosphatidylinositol 4-phosphate
PINK1 PTEN-induced putative kinase 1
PM Plasma membrane
PMDs Protein misfolding disorders
Pp1 Protein phosphatase 1
PRKN Parkin
PrP Prion protein
PS Phosphatidylserine
PS1/2 Presenilin-1/2 (PS1/2)
PTSD Post-traumatic stress disorder
RAB1 Ras-associated binding 1
RIDD Regulated IRE1-dependent decay
ROS Reactive oxygen species
RTK Receptor tyrosine kinase
S1P Site 1 protease
S2P Site 2 protease
SERCA Sarco/endoplasmic reticulum Ca2+-ATPase
Sigr1 Sigma-1 receptor
SNCA Synuclein Alpha gene
SNpc Substantia nigra pars compacta
SNPs Single nucleotide polymorphisms
SOCE Store operated Ca2+ entry
SOD1 Superoxide dismutase1
STIM Stromal-interacting molecule
TARDBP or TDP-43 TAR DNA-binding protein
TNF Tumor necrosis factor
TRAF2 TNF receptor-associated factor 2
TSE Transmissible spongiform encephalopathies
TUDCA Tauroursodeoxycholic acid
uORF Upstream open reading frame
UPR Unfolded protein response
VAP
VAPB
Vesicle-associated membrane protein-associated protein
Vesicle-associated membrane protein-associated protein B
VDAC1 Voltage-dependent anion selective channel protein 1
VMP1 Vacuole membrane protein 1
WT Wild type
XBP1 X-box binding protein 1
α-SYN α-synuclein