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. 2020 Aug 25;17(17):6175. doi: 10.3390/ijerph17176175

Table 5.

Dementia and Alzheimer’s disease.

Study Region(s)
Study Design
Quality Score (++,+,-)
Population Outcome Assessment Noise Source Noise Measures Noise Categories Effect Estimates;
Meta-Analysis (Yes, No with Reasons)
Andersson et al. 2018 [64] Sweden,
Cohort
(+)
n = 1721 (M = 985, F = 736)
55–85 years
Alzheimer’s disease and vascular dementia:
Three-step procedure: general examination, examination by specialists and diagnosed by specialist a
road Leq,24h <55 dB
≥55 dB
Odds Ratio
(adjusted)
Carey et al. 2018 [65] UK,
Cohort
(+)
n = 130,978 (M = 65 130, F = 65,848)
50–79 years
Alzheimer’s disease and vascular dementia:
Doctor’s diagnosis (from database)
road LN, 11 p.m.-7:00 a.m. Continuous analysis Odds Ratio
(adjusted)
Fuks et al. 2019 [67] Germany,
Cohort
(+)
n = 288
(females only)
74.2 years (±2.2)
Cognitive function according to CERAD-Plus battery road LDEN
LNIGHT
Odds Ratio
(adjusted)
Linares et al. 2017 [66] Spain,
longitudinal ecological time series study
(–)
n = 3,116,897 Dementia-related emergency
hospital admissions (related to organic psychoses: ICD-9 b)
road LN, 10:00 p.m.-8:00 a.m. Leq, 8:00 a.m.-10:00 p.m. Continuous analysis Correlation coefficient
no
Tzivian et al. 2016 [68] Germany
cross-sectional (analysis within cohort)
(+)
n = 2050
50–80 years
Mild cognitive impairment, test battery with ADAS and NAI c road LDEN
LN,10:00 p.m.-6:00 a.m.
Dichotomized (cut point 60 dB (LDEN) and 55 dB (LN)
<45 dB
≥45–<55 dB
≥55–<65 dB
≥65–<75 dB
≥75
Continuous
Odds Ratio
(adjusted)

ADAS = Alzheimer’s disease Assessment Scale, CERAD = Consortium to Establish a Registry for Alzheimer’s Disease NAI = Nuremberg Gerontopsychological Inventory, UK = United Kingdom; (a) Mini-Mental State Examination (MMSE) score of ≤23 and medical records; diagnosis according to the DSM-IV (Diagnostic and Statistical Manual of Mental Disorders, fourth edition) and NINCDS–ADRDA (National Institute of Neurological and Communicative Diseases and Stroke/Alzheimer’s Disease and Related Disorders Association) criteria) Mini-Mental State Examination (MMSE) and total score used; (b) ICD-9 codes: 290.0–290.2, 290.4–290.9, 294.1–294; (c) Diagnosis according to the criteria of Petersen [69]: presence of a subjective cognitive complaint, or presence of an objective cognitive impairment that did not fulfill the criteria for dementia, and activities of daily living were generally intact.