| AAG | Alkyl adenine DNA glycosylase |
| AAP | Assembly activating protein |
| AAV | Adeno-associated virus |
| ABE1.2 | First-generation adenine deaminase |
| ABE7.10 | Seventh-generation adenine base-editor |
| ABE8 | Eighth-generation adenine base-editor |
| AID | Activation-induced cytidine deaminase |
| APOBEC1 | Apolipoprotein B MRNA Editing Enzyme Catalytic Subunit 1 |
| AsCpf1 | Acidaminococcus sp. Cfp1 |
| LbCpf1 | Lachnospiraceae bacteriumare Cpf1 |
| Bps | Base-pairs |
| SaCas9 | Staphylococcus aureus Cas9 |
| BE | Base-editor |
| BER | Base excision repair |
| Cas | CRISPR-associated genes |
| CBE1 | First-generation cytosine base-editor |
| CBE2 | Second-generation cytosine base-editor |
| CBE4 | Fourth-generation cytosine base-editor |
| CjCas9 | Campylobacter jejuni Cas9 |
| Cpf1/Cas12a | Prevotella and Francisella1 |
| CRISPR | Clustered Regularly Interspaced Short Palindromic Repeats |
| dAsCpf1 | Catalytically inactive AsCpf1 |
| dCas9 | Catalytically deficient Cas9 |
| dLbCpf1 | Catalytically inactive LbCpf1 |
| DSB | Double-strand DNA break |
| CBE | Cytosine base-editor |
| ABE | Adenine base-editor |
| PE | Prime editor |
| Indel | Insertion or deletion |
| NHEJ | Non-homologous end joining |
| GDS | Gene delivery system |
| HDR | Homology directed repair |
| HEK293 | Human embryonic kidney cells |
| HF | High-fidelity version of dCas9 |
| HT1 | Hereditary tyrosinemia type 1 |
| iPSCs | Induced pluripotent stem cells |
| ITR | Inverted terminal repeats |
| M-MLV RT | Moloney murine leukemia virus reverse transcriptase |
| nCas9 | Cas9 nickase |
| NLS | Nuclear Localization Signal |
| ORF | Open reading frame |
| PACE | Phase assisted continuous evolution |
| PAM | Protospacer adjacent motif |
| gRNA | Guide RNA |
| PANCE | Phage-assisted non-continuous evolution |
| PBS | Primer binding site |
| PE1 | First-generation prime editor |
| pegRNA | Prime editing guide RNA |
| pmCDA1 | Petromyzon marinus cytidine deaminase 1 |
| rAAV | Recombinant AAV |
| RK | Rhodopsin kinase |
| RP | Retinitis pigmentosa |
| RT | Reverse Transcriptase |
| ScCas9 | Streptococcus canis Cas9 |
| sgRNA | Small guide RNA |
| SpCas9 | S. pyogenes’ Cas9 |
| Spy-mac | Cas9 fusion derived from Streptococcus pyogenes and Streptococcus macacae |
| TadA | tRNA adenosine deaminase |
| TALEN | Transcription activator-like effector nucleases |
| tracrRNA | Trans-activating RNA |
| UNG | Uracil N-glycosylate |
| ZFN | Zinc-finger nuclease |