PO2
|
Partial Oxygen Pressure |
HAPH |
High-Altitude Pulmonary Hypertension |
HPV |
Hypoxic Pulmonary Vasoconstriction |
eNOS |
Endothelial Nitric Oxide Synthase |
IL-1 |
Interleukin 1 |
IL-6 |
Interleukin 6 |
PH |
Pulmonary Hypertension |
PO |
Pressure Overload |
RVH |
Right Ventricular Hypertrophy |
RV |
Right Ventricle |
RHF |
Right Heart Failure |
HF |
Heart Failure |
ROS |
Reactive Oxygen Species |
O2·−
|
Superoxide Anion |
·OH |
Hydroxyl Radical |
ROO· |
Peroxyl Radicals |
RO· |
Alkoxy Agents |
HOCl |
Hypochlorous Acid |
O3
|
Ozone |
1O2
|
Singlet Oxygen |
H2O2
|
Hydrogen Peroxide |
ONOO−
|
Peroxynitrite |
SODs |
Superoxide Dismutases |
CAT |
Catalase |
GSH-PX/RX
|
Glutathione Peroxidase/Reductase |
MPTP |
Mitochondrial Permeability Transition Pore |
NF-kB |
Nuclear Factor-Kappa B |
HIF-1α |
Hypoxia-Inducible Factor-1α |
Ca2+
|
Calcium |
SERCA2a |
Sarcoplasmic Reticulum Ca2+ ATPase |
Na+
|
Sodium |
NADPH |
Nicotinamide Adenine Dinucleotide |
AP-1 |
Activator Protein 1 |
MCP-1 |
Monocyte Chemoattractant Protein-1 |
Ang II |
Angiotensin II |
BNP |
Brain Natriuretic Protein |
MAPKs |
Mitogen-Activated Protein Kinases |
JNK |
C-Jun N-Terminal Kinases |
ERK |
Extracellular Signal-Regulated Kinases |
IL-1β |
Interleukin 1β |
SDF-1 |
Stromal Cell-Derived Factor 1 |
CXCR-4 |
C-X-C Chemokine Receptor Type 4 |
PKC |
Protein Kinase C |
A-SMA |
Smooth Muscle Actin A |
MRTF-A |
Myocardin-Related Transcription Factor A |
ET-1 |
Endothelin-1 |
TGF-α |
Transforming Growth Factor α |
TGF-β |
Transforming Growth Factor β |
STIM1 |
Stromal Interacting Molecule-1 |
TNF-A |
Tumor Necrosis Factor A |
HIMF |
Hypoxia-Induced Mitogenic Factor |
PHD |
Prolyl Hydroxylase |
VHL |
Von Hippel-Lindau |
MΦ |
Monocyte/Macrophage |
OSM |
Oncostatin-M |
iNOS |
Inducible Nitric Oxide Synthase |
ACE |
Angiotensin-Converting Enzyme |
ETa
|
Endothelin A Receptor |
ETb
|
Endothelin B Receptor |
RAAS |
Renin-Angiotensin-Aldosterone-System |
GLUT4 |
Glucose Transporter 4 |
GPx |
Glutathione peroxidase |