Table 1.
Alleviation of EAE clinical symptoms by iTBS and cTBS in rats.
| Experimental Groups | Maximal Clinical Severity Score | Paralysis | Body Mass Loss and Gained | |||
|---|---|---|---|---|---|---|
| Started (dpi) | Lasted (Days) | Started (dpi) | Lasted (Days) | Min. Weight (%) |
Gained Weight (%) |
|
| EAE EAE+i/cTBSsh |
11.8 | 3.08 ± 0.97 | 12 | ~3.5 ~2.5 |
~70 (14th dpi) | ~96 (20–24th dpi) |
| EAE+i/cTBS | 11.5 | 2.79 ± 0.76 | 11.8 | ~1.7 a | ~81 (15th dpi) | ~90 (20–24th dpi) |
ap < 0.05; Legend: EAE—rats with experimental autoimmune encephalomyelitis; EAE + i/cTBS [EAE + iTBS, and EAE + cTBS groups—EAE rats subjected to iTBS and cTBS]; EAE + i/cTBSsh [EAE + iTBSsh and EAE + cTBSsh—EAE rats subjected to iTBS’s and cTBS’s noise artifact (sham-treated EAE rats)].