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. 2020 Aug 28;21(17):6244. doi: 10.3390/ijms21176244

Figure 3.

Figure 3

Single-cell RNA sequencing of the lungs reveals that THC upregulates genes associated with apoptosis in SEB-challenged mice. Mice were treated with SEB+Veh or SEB+THC, as described in the Figure 1 legend. (A): scRNA-seq t-Distributed Stochastic Neighbor Embedding (tSNE) colored by cell type. (B): scRNA-seq tSNE split by sample ID and colored by cell type. (C): Violin plots of Bad expression amongst the clusters in SEB+Veh vs. SEB+THC. (D): Violin plots of Bax expression amongst the clusters in SEB+Veh vs. SEB+THC. (E): Violin plots of the Cox4i1c expression amongst the clusters in SEB+Veh vs. SEB+THC. (F): Violin plots of the Apopt1 expression amongst the clusters in SEB+Veh vs. SEB+THC. (G): Violin plots of the Casp3 expression amongst the clusters in SEB+Veh vs. SEB+THC. (H): Violin plots of Slc25a3 and Slc25a39 in CD8+ and CD4+ T cells.