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. 2020 Aug 28;21(17):6244. doi: 10.3390/ijms21176244

Figure 5.

Figure 5

THC treatment in SEB-injected mice results in altered miR expression in lung-infiltrating MNCs. Mice were treated with SEB+Veh or SEB+THC, as described in the Figure 1 legend. MNCs from the lungs were isolated and screened for miR expression. (A): IPA pathways and relationships between miRs and genes in lung MNCs. (B): qRT-PCR validation of miR-185-3p in lung-infiltrating MNCs. (C): Seed sequence alignments between miR-185-3p and Bad, Hrk, Runx3, Cox4 and Nkiras2. (D–I) qRT-PCR validation of miR-185-3p targeted genes Bad (D), Bax (E), Hrk (F), Runx3 (G), Cox4 (H), and Nkiras2 (I) in lung-infiltrating MNCs. Statistical significance is depicted as * p < 0.05, *** p < 0.001, **** p < 0.0001 between the compared groups.