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. 2020 Aug 31;21(17):6289. doi: 10.3390/ijms21176289

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Classification of normal and cancerous thyroid tissue cores based on MSI-registered spectra. Results of a core class prediction are presented as actual numbers (a relative frequency of specific results is color-coded according to the color scale); the last column represents the total number of cores. Presented are: a single-pixel approach for 1536 features (panel A) and 147 features (panel B), a mean spectrum approach for 1536 features (panel C), and a hybrid approach for 1,536 features (panel D).