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Natural killer cell dysregulation in (a) systemic diseases; (b) hematologic malignancies; (c) SARS-CoV-2. (a) Immune imbalance in atherosclerosis, autoimmunity and ageing leads to excess inflammation; (b) Hematologic malignancies trigger both excess inflammation and immune invasion; (c) SARS-CoV-2 and respiratory syncytial virus (RSV) trigger immune imbalances which result in a disproportionate inflammatory response.
