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. 2020 Aug 26;21(17):6173. doi: 10.3390/ijms21176173

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Role of oxidative signal inducible 1 (OXI1) in retrograde signaling in mature mesophyll cells. OXI1 in response to reactive oxygen species (ROS) induces biosynthesis of jasmonic acid (JA) and induces programmed cell death (PCD) through MPK11/MPK13-mediated pathway. JA induces expression of ICS1. Crosstalk between SA and JA along with endoplasmic reticulum (ER)-associated proteins DEFENDER AGAINST CELL DEATH (DAD1)/DAD2 regulates expression of OXI1. Dotted lines represent pathways which lack experimental evidence or exact nature of indicated regulation is still unknown.