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. 2020 Aug 21;21(17):6031. doi: 10.3390/ijms21176031

Figure 5.

Figure 5

Models showing amyloid fibril formation and inhibition by RA. The mSAA oligomer can assemble further to form higher order oligomers, then rapidly recruit other monomers from the surroundings to assemble amyloid fibrils. RA can inhibit an oligomer from forming a higher order oligomer or/and amyloid fibrils in nucleation and elongation phases, but cannot degrade the formed fibrils.