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. 2020 Aug 19;13(17):3668. doi: 10.3390/ma13173668

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Pore structure-dependent degradability of nanoparticles within normal cells and cancer cells scheme: (A) redox reaction of the disulfide bond and GSH; (B) illustration of the organic-inorganic hybrid composition of drug delivery MONs, with small or large pores, and its degradation in normal cells with low level of GSH; or within cancer cells containing high level of GSH. Reproduced from [43] (https://doi.org/10.1021/acs.chemmater.6b03896), with permission from the American Chemical Society.