Table 1.
Evaluation of inflammatory markers and cytokeratins expression in soft tissues facing machined or nanopored laser-treated healing abutment.
| Epithelium | Subepithelial Connective Tissue | |||
|---|---|---|---|---|
| Machined-Surface | Laser Treated Surface | Machined-Surface | Laser Treated Surface | |
| Inflammatory Markers | ||||
| MMP-9 | 13.8 ± 2.1 | 1.4 ± 1.1 * | 41.1 ± 9.2 | 2.3 ± 1.1 * |
| ICAM-1 | 76.8 ± 8.1 | 23.1 ± 5.9 * | 75.1 ± 6.3 | 7.0 ± 1.2 * |
| Structural Proteins of keratinocytes | ||||
| CK-18 | 80.3 ± 6.5 | 8.1 ± 1.3 * | - | - |
| CK-19 | 84.1 ± 8.3 | 4.6 ± 3.4 * | - | - |
| DSG-3 | 14.2 ± 4.2 | 86.7 ± 6.1 * | ||
Values represent the % of positive in immunohistochemical analysis, calculated as the mean of five different determinations in randomly chosen sections for each specimen. Values are expressed as mean ± SD. * indicates statistical difference (p < 0.001) between the region of the gingiva adherent to the laser-treated vs. machined- surfaces.