OA	Osteoarthritis
CRISPR	Clustered Regularly Interspaced Short Palindromic Repeats
Cas	Cas nuclease
crRNA	CRISPR RNA
tracrRNA	trans-activating crRNA
PAM	protospacer adjacent motif
sgRNA	single guide RNA
MSC	Mesenchymal stem cells
miRNA	Micro RNA
EV	Extracellular vesicles
IL-1β	Interleukin 1 beta
TNFα	Tumor Necrosis Factor
Hac	Human articular cartilage
IL1-R1	IL-1β cytokine receptor 1
BGLAP	Osteocalcin
Has2	Hyaluronan synthase 2
PRG4	Lubricin
Runx2	Runt Related Transcription Factor 2
Hrdl	E3 ubiquitin-protein ligase hrd-like protein 1
Mmp13	Matrix metalloprotein 13
Cx43	Connexin 43
Cbx4	Chromobox 4
Foxd1	Forkhead box D1
YAP	Yes-associated protein 1
NHEJ	Non-homologous end joining
HDR	Homology Directed Repair
TALENs	Transcription activator-like effector nucleases
ZFN	Zinc finger nucleases