Figure 15.

A schematic representing a multi-modal Janus nanoparticulate system composed of a SPION/MSN core/shell face and Au nanoparticle face. T₂ MRI contrast capabilities arise from the encapsulated SPION with Au nanoparticles providing the possibility for CT imaging. As shown in this schematic, the system is functionalised with a fluorescent dye (Alexa Fluor^® 647) for optical imaging in addition to cRDG for active tumour targeting. Reprinted with permission from reference [178]. Copyright (2018) American Chemical Society.