Table 6.

Examples of phenolics extracted by supercritical CO_2.

Compounds	Plant Material	Studied Parameters	Country	References
Flavonoids	Strobilanthes crispus (Pecah Kaca) leaves	Pressure: 100, 150 and 200 bar Temperature: 40, 50 and 60 °C Dynamic extraction time: 0, 40, 60 and 80 min	Malaysia	[104]
	Odontonema strictum leaves	Pressure: 200 and 250 bar Temperature: 55–65 °C CO2 flow: 15 g/min Co-solvent: ethanol 95% Extraction time: 210–270 min	Burkina Faso	[106]
Flavonoids (Tiliroside)	Tilia L. flower	Pressure: 100–220 bar Temperature: 45–80 °C Time: 20–60 min	Poland	[107]
Total phenolic compounds, total flavonoids	Radish leaves	Pressure: 300 and 400 bar Temperature: 35, 40, and 50 °C CO2 flow rate: 10 g/min Co-solvent: ethanol	Argentina	[34]
Flavonoids (hesperidin, nobiletin, and tangeretin)	Citrus genkou peels	Pressure: 100–300 bar Temperature: 40–80 °C	Japan	[108]
Total phenols	Strawberry (Arbutus unedo L.)	Pressure: 150, 250, 350 bar Temperature: 40, 60, 80 °C Co-solvent: ethanol (0, 10, 20%) CO2 flow rate: 15 g/min Extraction time: 60 min	Turkey	[46]
Fatty acid	Pomegranate seed oil	Pressure: 240, 280 and 320 bar Temperature: 40,50 and 60 °C CO2 flow rate: 133.3 g/min Extraction time: 180 min	Italy	[42]
	Yacon leaves	Pressure: 150–250 bar Temperature: 30–70 °C Co-solvent: ethanol	Brazil	[109]
Phenolic compounds	Hibiscus sabdariffa	Pressure: 150–350 bar Temperature: 40 to 60 °C Co-solvent: ethanol 7–15% Total flow: 25 g/min Extraction time: 90 min	Spain	[110]
Tocotrienols	Annatto seed	Pressure: 100, 170, 240 and 310 bar Temperature: 40 and 60 °C CO2 densities: 290–915 kg/m3	Brazil	[65]
Tocopherol	Quinoa (Chenopodium quinoa Will)	Pressure: 200–400 bar Temperature: 40–60 °C	Spain	[111]