Figure 4.

Chemical shift perturbations in the NH region of the ¹H NMR spectra at 298 K in 9:1 (v/v) H₂O/D₂O induced by dodecylphosphocholine (DPC): Sets of 1D ¹H NMR spectra of a 1 mM solution of peptides were acquired with 128 scans. One-dimensional ¹H NMR spectra of Pro9-3 were recorded with 9 different concentrations of DPC from 10 to 11 ppm (A), and 1D ¹H NMR spectra of Pro9-3 (B) and Pro10-1 (C) from 7 to 11 ppm were recorded for six different concentrations of DPC. Changes in chemical shifts and line broadenings in the spectra of the peptides upon addition of DPC indicate conformational changes and interactions with DPC.