mAb |
Monoclonal antibody |
CHI3L1 |
Chitinase-3-like 1 |
CLP |
Chitinase-like protein |
ELISA |
Enzyme-linked immunosorbent assay |
EC
50
|
Half maximal effective concentration |
IgG |
Immunoglobulin G |
Fab |
Antigen-binding fragment |
scFv |
Single-chain variable fragment |
SEC |
Size-exclusion chromatography |
PTS |
Protein thermal shift |
T
m
|
Melting temperature |
K
D
|
Equilibrium dissociation constant |
IPTG |
Isopropyl β-D-1-thiogalactopyranoside |
PBS |
Phosphate-buffered saline |
SDS-PAGE |
Sodium dodecyl sulfate-polyacrylamide gel electrophoresis |
CDR |
Complementarity-determining region |
FR |
Framework |
VH |
Heavy-chain variable domain |
VL |
Light-chain variable domain |
CL |
Light-chain constant domain |
BLI |
Bio-layer Interferometry |