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Multi-omics approach to ASD. ASD is a multifactor disease that includes genetic and environmental factors. The phenotype of ASD determines abnormal neurodevelopment with alteration in neurotransmitters. Furthermore, ASD is characterized by mitochondrial dysfunction, oxidative stress, inflammation and abnormal immune regulation. All of these dysfunctions produce possible biomarkers that could be identified by a new multi-omics approach to studying ASD.
