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. 2020 Aug 29;21(17):6262. doi: 10.3390/ijms21176262

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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The temporal course of intraocular pressure (IOP) from the first till 42 days after uniocular (Right eye) microbead injection. In the Right eye there is a significant increase in the IOP immediately after glaucoma induction. In the Left untreated eye, IOP remains unchanged and is maintained within a range of pre-injection values. AAV2-BDNF administration to the Right eye preceded glaucoma induction by 3 weeks. Data are expressed as mean ± SD from 8 (glaucoma group) and 7 (AAV2-BDNF+ glaucoma group) rats. * p < 0.01, different from intact and between time-points (except for day 3 vs. 7). For the comparison of IOP levels in time, a t-test for dependent variables was used.