Table 1.

Roles of FASN in various malignancies.

Role of FASN	Function	Test Model	Tumor Type	Reference
Promote	Lipogenesis	In vitro	Breast	[70]
	Signal transduction	In vitro, Mouse	Breast, Prostate, Colorectal, Non-small Lung	[40,71,75,76]
	Cytoskeleton remodeling	In vitro	Cervical	[72]
	Mitochondria respiration	In vitro, Mouse	Colorectal, Melanoma, Breast	[77,78,79]
	Fatty Acid Oxidation	In vitro, Mouse	Melanoma, Breast, Colorectal	[78,79,80]
	Mitochondria fusion	In vitro	Prostate, Breast	[81]
	Lipolysis	In vitro	Breast	[82]
	DNA repair	In vitro	Breast, Pancreatic	[83]
	Cell cycle	In vitro	Cervical	[9]
	Glycolysis	In vitro	Colorectal, Breast, Non-Hodgkin Lymphoma	[77,84,85]
	Cell migration	In vitro	Breast	[84]
Repress	DNA repair	In vitro	Non-small Lung	[86]
	Unfolded Protein Response	In vitro	Colorectal	[87]
	Programmed cell death	In vitro	Breast, Pancreatic	[88,89]