Table 2.

In vitro affinities of compounds 1 to 7 for α1-ARs, D₂ and 5HT_2C receptors [73,75,76].

Compound	Receptor Ki (nM)
	α1A	α1B	α1D	D2	5HT2C
1	0.37	0.33	0.66	0.45	0.55
2	0.23	1.1	2.0	140	330
3	3.0	6.0	8.6	310	1500
4	0.16	6.4	15	220	-
5	0.52	1.9	2.5	120	-
6	0.37	0.33	0.66	0.45	0.51
(R)-7	0.43	0.27	0.64	31	8.0
(S)-7	0.16	0.20	0.21	4.5	93