. 2020 Aug 24;205(7):1743–1751. doi: 10.4049/jimmunol.2000482

Table I. Clinical information.

MG Patients
Sample No.	Gender/Age (y)^a	MGFA Classification	MGFA Classification^a	AChR Level, nmol/L^a	Disease duration (y)^a	Treatments	Thymectomy	Thymoma	CD45⁺CD20⁺CD4⁻ B cells
Sample No.	Gender/Age (y)^a	MGFA Classification	MGFA Classification^a	AChR Level, nmol/L^a	Disease duration (y)^a	Treatments	Thymectomy	Thymoma	Intracellular SVN⁺%	Extracellular SVN⁺%
1	F/26	IVa	IIIa	7.0	1	Pred	X		1.52	1.52
2	M/73	IIIb	IIb	9.0	7	Pred			0.99	1.39
3	M/71	IVa	IIa	91.0	0.6	Pred, Pyr			1.26	1.45
4	F/42	IIIa	IIIa	13.1	0.25	Pred, Pyr	X	B2	1.68	1.31
5	F/21	IVa	IIIa	58.0	8	Pred, Pyr	X		1.44	2.91
6	F/41	II	IIa	0.9	3	None			0.37	2.00
7	M/75	IIIa	IIa	26.7	0.25	Pred < 1 mo			3.45	1.72
8	F/77	V	MR	31.6	2	Pred, Pyr	X	B	2.84	3.50
9	M/59	I	I	0.2	0.33	None			0.29	0.56
10	M/87	IVb	IIa	25.0	0.33	Pred		B2	12.80	2.08
11	M/71	IIIb	MR	19.0	11	Myc, IVIG			5.51	4.96
12	M/63	IIIa	R		7	Aza	X	B1	4.14	1.80
13	M/73	IIIa	MR	45.0	2	Myc, Pred			1.11	2.88
14	M/51	IIIb	IIa	0.0	3	Myc, Pred			5.78	1.20
15	F/50	I	I	33.0	10	Pyr			19.00	4.19
16	M/56	IVa	MR	55.0	1	Myc, Pred			0.99	1.87
17	M/65	I	I	2.7	0.2	Pyr			1.17	2.10
18	M/41	IV	II	1.2	25	Pred, Pyr	X		6.59	2.37
19	F/57	IIa	CSR	5.4	2	None	X	AB	15.00	1.61
20	F/49	IIIa	MR	11.9	6	Myc	X	AB	10.70	0.55
21	M/65	I	I	15.0	1.5	Myc, Pred			4.37	1.16
22	M/61	I	I		0.75	Pyr			1.67	0.76
23	F/26	I	I	0.3	17	Pyr			5.49	1.29
24	M/69	I	I		0.9	Pyr			8.87	3.62
25	F/50	IIa	IIa	2.2	23	Pyr			17.50	0.87
26	F/56	I	CSR	2.5	1.2	Pyr			1.20	1.45
27	M/92	I	I	5.2	0.3	None			6.77	1.60
28	F/32	IIIa	IIa	1.0	1.5	Pred, IVIG	X		4.80	1.47
29	M/30	IIa	IIa	18.0	1.5	Pyr			5.52	0.57

Other Neurological Disease Patients
Sample No.	Gender/Age (y)^a	Diagnosis	CD45⁺CD20⁺CD4⁻ B cells
Sample No.	Gender/Age (y)^a	Diagnosis	Intracellular SVN⁺%	Extracellular SVN⁺%
1	F/61	No evidence of neurologic disease	0.09	0.95
2	F/48	Radiculopathy	0.86	0.46
3	F/61	Migraine	3.04	1.42
4	F/26	Syncope	2.10	1.76
5	M/28	No evidence of neurologic disease	1.27	0.56
6	M/48	Headaches	0.72	0.92
7	M/45	Migraine	2.51	1.58
8	M/60	Refractive error	1.75	1.55
9	M/43	Ulnar neuropathy	2.33	1.90
10	M/69	Parkinson disease	0.56	1.04
11	M/40	Bell palsy	1.37	0.86
12	M/47	Cervical radiculopathy	2.80	0.47
13	F/47	Chronic cluster headache	2.42	0.99
14	M/54	Bilateral carpal tunnel syndrome	0.57	0.56
15	F/54	Episodic migraine	1.93	0.42

^{^a}

At the time of blood collection.

AChR, acetylcholine receptor; Aza, azathioprine; F, female; IVIG, i.v. Ig; M, male; MGFA, Myasthenia Gravis Foundation of America; Myc, mycophenolate; Pred, prednisone; Pyr, pyridostigmine; SVN, survivin.