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Estimated exposure doses for acute nose-only exposure.
| ENM | Deposition fraction in pulmonary region | Estimated dosea |
|||
|---|---|---|---|---|---|
| By mass mg/kg | By animal μg/mouse | By lung mass μg/gc | By lung surfaceb ng/cm2 | ||
| ZnO | 0.21 | 0.23 | 4.7 | 39.0 | 6.9 |
| CuO | 0.22 | 0.25 | 4.9 | 41.1 | 7.2 |
| V2O5 | 0.20 | 0.25 | 4.9 | 41.1 | 7.2 |
| WO3 | 0.14 | 0.14 | 2.8 | 22.5 | 4.1 |
Assumes 165 breaths/min, tidal volume of 0.15 mL, and 20 g/mouse body mass.
680 cm2 surface area.
Wet weight of whole lungs used in this estimation was 120 mg.
