Fig.2.

Loss of in vitro endothelial barrier function. Human endothelial cells were exposed to plasma from traumatic hemorrhagic shock patients collected at admission at the emergency department (ED), intensive care unit (ICU), 24 hours (ICU+24 h) after admission at the ICU and from controls (all n = 8). Endothelial resistance after plasma exposure over time (A) and after 2 hours of plasma exposure (B). A: Data represent mean and were tested with a two-way ANOVA with Bonferroni post-hoc analysis. B: Data represent mean±SD and were tested with a one-way ANOVA with Bonferroni post-hoc analysis. ^*p < 0.05, ^**p < 0.01, ^***p < 0.001 compared to ED admission.