Table 1.
Patients (eyes) | Spearman's rho with VA after 1 year | p-value | |
---|---|---|---|
Age at ON onset | n = 32 (36) | 0.404 | 0.0146 |
AQP4-IgG titer before starting IVMP | n = 23 (27) | 0.237 | 0.23 |
ON-involved segments in orbital MRI (0–6) | n = 26 (28) | 0.669 | <0.0001 |
Treatments in the acute phase of ON | |||
Days from ON onset to starting IVMP | n = 32 (36) | 0.502 | 0.0018 |
Cycles of IVMP | n = 32 (36) | −0.235 | 0.17 |
Cycles of IVMP among those treated | n = 29 (32) | −0.013 | 0.95 |
Days from ON onset to starting PLEX | n = 32 (36) | 0.132 | 0.44 |
Cycles of PLEX | n = 32 (36) | −0.156 | 0.36 |
ON-involved eyes further treated by adjunctive PLEX after IVMP pulse therapy | |||
Days from ON onset to starting PLEX | n = 19 (21) | 0.21 | 0.37 |
Cycles of PLEX | n = 19 (21) | −0.25 | 0.28 |
The p-values shown are the results of the test of no correlation.
AQP4-IgG, anti-aquaporin-4 autoantibody; IVMP, intravenous methylprednisolone; ON, optic neuritis; PLEX, plasma exchange; VA, visual acuity.