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. 2020 Sep 2;11:932. doi: 10.3389/fneur.2020.00932

Table 1.

Correlation coefficients between studied variables and visual outcome.

Patients (eyes) Spearman's rho with VA after 1 year p-value
Age at ON onset n = 32 (36) 0.404 0.0146
AQP4-IgG titer before starting IVMP n = 23 (27) 0.237 0.23
ON-involved segments in orbital MRI (0–6) n = 26 (28) 0.669 <0.0001
Treatments in the acute phase of ON
Days from ON onset to starting IVMP n = 32 (36) 0.502 0.0018
Cycles of IVMP n = 32 (36) −0.235 0.17
Cycles of IVMP among those treated n = 29 (32) −0.013 0.95
Days from ON onset to starting PLEX n = 32 (36) 0.132 0.44
Cycles of PLEX n = 32 (36) −0.156 0.36
ON-involved eyes further treated by adjunctive PLEX after IVMP pulse therapy
Days from ON onset to starting PLEX n = 19 (21) 0.21 0.37
Cycles of PLEX n = 19 (21) −0.25 0.28

The p-values shown are the results of the test of no correlation.

AQP4-IgG, anti-aquaporin-4 autoantibody; IVMP, intravenous methylprednisolone; ON, optic neuritis; PLEX, plasma exchange; VA, visual acuity.