Table 1.
Composite Z scores.
Individual mouse | Young adult mice | Elderly mice | ||
---|---|---|---|---|
Control group | Surgery group | Control group | Surgery group | |
1 | 0.926 | 3.725 | 0.131 | -3.768^ |
2 | 1.828 | -5.265^* | -1.232* | -0.787 |
3 | 0.074 | -0.605 | -0.359 | -2.004^ |
4 | 0.015 | -0.803 | 0.243 | -2.093^ |
5 | -0.596 | 1.700 | -0.884 | -4.131^* |
6 | 0.390 | -0.337 | -0.293 | -2.034^ |
7 | 0.800 | 1.051 | 0.221 | -3.113^* |
8 | -2.067^ | -7.026^* | -0.535 | -2.933^ |
9 | 0.226 | -0.641 | 1.506 | -0.180 |
10 | -0.334 | -1.240 | 0.782 | -2.388^* |
11 | 1.775 | -0.842 | 0.045 | -0.542 |
12 | -1.333 | -6.122^* | 0.759 | -2.061^ |
13 | -0.659 | 1.651 | -2.619^* | 0.243 |
14 | 1.334 | -4.273^* | 0.526 | -3.510^* |
15 | -0.811 | -0.015 | 1.305 | -3.017^* |
16 | 0.408 | -0.406 | 0.576 | -2.479^* |
17 | -0.482 | -4.268^* | -1.283 | -2.832^* |
18 | 0.662 | -2.619^ | 0.810 | -1.467 |
19 | -0.844 | -0.980 | -0.590 | -1.064 |
20 | -0.695 | -0.876 | 0.892 | -0.212 |
21 | -0.617 | -4.168^* | -0.921 |
Different mice were used for different groups. No mice were used in two study groups. The number assigned to each mouse in a group was randomly performed and were not performed in a paired format between control and surgery groups. Negative Z scores refer to decreased learning and memory after surgery (surgery group) or in the second set of tests compared to the first set of tests (control group). Positive Z scores refer to improved learning and memory after surgery (surgery group) or in the second set of tests compared to the first set of tests (control group). ^ indicates a mouse with cognitive decline as identified by composite Z score.
indicates a mouse with cognitive decline as identified by Z scores of at least two individual tests.